The Benefits of Sublingual Delivery – How Manufacturers Are Meeting Demand
Sublingual drug delivery, where a drug is positioned under the tongue for absorption, offers various advantages over the conventional oral route. Manufacturers are actively innovating to meet the growing demand for this beneficial delivery method. Benefits of Sublingual Delivery Quick Onset of Action The region under the tongue is highly vascular, meaning drugs absorbed here bypass the gastrointestinal tract and liver, reaching the bloodstream directly. This results in a much quicker onset of therapeutic effects, which is crucial in cases requiring immediate relief. Evading First-Pass Metabolism Swallowed drugs pass through the liver before entering the systemic circulation. The liver enzymes break down most of the drug, lowering its bioavailability and potency. Sublingual administration bypasses this process, leading to increased bioavailability and allowing for lower doses to produce the desired effect. Better Bioavailability Because first...